CHEM 0002B. Introduction to Chemistry II
Units: 5
Prerequisite: Completion of CHEM 2A with grade of "C" or better
Advisory: Eligibility for ENGL 1A
Hours: 126 (72 lecture, 54 laboratory)
Designed to meet the requirements for certain nursing, dental hygiene, physical therapy, agriculture, and forestry programs (Organic and Biochemistry). A study of the major classes of organic compounds, including nomenclature structure, properties, and isomerism. Emphasizes the chemistry and metabolism of carbohydrates, lipids, and proteins, including nucleo-protein and enzymes through related lecture and laboratory exercises. (C-ID CHEM 102) (CSU, UC-with unit limitation)
CHEM 0002B - Introduction to Chemistry II
http://catalog.sierracollege.edu/course-outlines/chem-0002b/
Catalog Description DESCRIPTION IS HERE: Prerequisite: Completion of CHEM 2A with grade of "C" or better Advisory: Eligibility for ENGL 1A Hours: 126 (72 lecture, 54 laboratory) Description: Designed to meet the requirements for certain nursing, dental hygiene, physical therapy, agriculture, and forestry programs (Organic and Biochemistry). A study of the major classes of organic compounds, including nomenclature structure, properties, and isomerism. Emphasizes the chemistry and metabolism of carbohydrates, lipids, and proteins, including nucleo-protein and enzymes through related lecture and laboratory exercises. (C-ID CHEM 102) (CSU, UC-with unit limitation) Units 5 Lecture-Discussion 72 Laboratory 54 By Arrangement Contact Hours 126 Outside of Class Hours Course Student Learning Outcomes Demonstrate proficiency in solving problems and analyzing data related to functional groups in organic chemistry. Demonstrate proficiency in solving problems and analyzing data related to biochemical molecules. Apply biochemical principles to metabolism. Demonstrate proficiency in scientific communication. Course Content Outline 1. saturated hydrocarbons 2. unsaturated hydrocarbons 3. alcohols, phenols, and ethers 4. aldehydes and ketones 5. carboxylic acids, esters, and other acid derivatives 6. amines and amides 7. carbohydrates 8. carbohydrate metabolism 9. biological energy production 10 lipids 11. lipid metabolism 12. proteins 13. protein metabolism 14. enzymes 15. nucleic acids Course Objectives Course Objectives On written examinations, on laboratory exercises, or in laboratory experiments students will: Lecture Objectives: 1. compare and contrast the properties of organic and inorganic compounds; 2. determine the geometry, shape, and polarity of an organic molecule; 3. diagram the structures and provide names for alkanes, alkenes, alkynes, aromatic compounds, alcohols, ethers, phenols, thiols, aldehydes, ketones, carboxylic acids, salts of acids, esters, anhydrides, amines, amides; 4. identify esters; 5. diagram isomers of organic compounds; 6. describe the physical properties and chemical properties for alkanes, alkenes, alkynes, aromatic compounds, alcohols, ethers, phenols, thiols, aldehydes, ketones, carboxylic acids, salts of acids, esters, anhydrides, amines, amides, aldehydes, ketones, carboxylic acids, salts of acids, esters, anhydrides, amines, amides; 7. explain the characteristics required for a molecule to exhibit cis-trans isomerism; identify and name cis-trans isomers; 8. identify important alcohols and ethers and their use; 9. write chemical reactions for alkanes, alkenes, alkynes, aromatic compounds, alcohols, ethers, phenols, thiols, aldehydes, ketones, carboxylic acids, listing all reactants and catalyst, if necessary, and predict products for each type of reaction; 10. write the chemical reactions for the synthesis and hydrolysis of hemiacetals, acetals, esters, anhydrides, and amides; 11. identify the general structure and function of important alkaloid drugs; 12. draw the basic structure of an amino acid; identify amino acids as polar, nonpolar, acidic, or basic; 13. draw the structure of a short polypeptide and identify the peptide bonds; 14. name and describe the four levels of protein structure and the intermolecular force(s) stabilizing each level; 15. compare and contrast the structure and functions of globular and fibrous proteins; 16. describe denaturation and explain how denaturing agents act at the molecular level to denature a protein; 17. explain amino acid utilization in the body; 18. describe the structure, properties, and role of enzymes; 19. explain the factors that affect enzyme activity; 20. explain the biological mechanisms for activating and regulating enzymes; 21. discuss how enzymes are used in medical diagnosis and treatment; 22. explain the concept of steroisomerism and its occurrence and significance in nature; sketch structures for the optical isomers of a compound; 23. identify the structures of the most common monosaccharides; 24. compare the occurrence in nature, the structural components, and type of bonding found in disaccharides and polysaccharides; 25. identify a carbohydrate as reducing or nonreducing; 26. identify the criteria that categorizes a substance as a lipid; 27. compare and contrast the structural characteristics and physical properties of a solid fat and a liquid fat; 28. diagram a generalized structure showing the components and type of bonds found in triglycerides, waxes, phosphoglycerides, sphingolipids, and glycolipids; explain the role of each of these compounds in biological systems; 29. list the types of compounds containing the steroid ring system; explain the physiological role of each type of compound in biological systems; 30. write a saponification reaction and sketch the structure of a soap; 31. compare and contrast the role of soap and bile as emulsifying agents in terms of structure, mode of action, and function; 32. describe the structure of the cell membrane; 33. explain the mechanism by which metabolites are transported across the cell membrane; 34. identify the structural features of eicosanoids; discuss the function of prostaglandins, leukotrienes, thromboxanes; 35. describe the mechanism for lipid transport and storage in biological systems, including the synthesis, structure, and function of chylomicrons, HDL, LDL, VLDL; 36. describe the pathways by which carbohydrates, lipids, and proteins are metabolized and the location of each of these pathways in the cell, including glycogenesis, glycolysis, Krebs cycle, B-oxidation, and urea cycle; 37. explain why acetyl CoA is considered a central molecule in metabolism; 38. explain the mechanism and purpose of the electron transport system and oxidative phosphorylation; 39. determine the number of high-energy ATPs generated from the metabolism of a given carbohydrate or fat; 40. explain the conditions under which ketoacidosis occurs and the resulting impact on physiological systems; 41. describe the anabolic processes of gluconeogenesis, glycogenesis, and fatty acid synthesis; 42. explain the link between DNA and heredity; 43. describe the structural components and type of bonds found in DNA and RNA; 44. explain the genetic code; 45. describe the three types of RNA and the function of each in biological systems; 46. explain the steps involved in the processes of DNA replication, RNA transcription, and translation; 47. explain the mechanisms for regulation of genetic expression; 49. explain the different types of mutation; 50. perform research on a topic using library or internet resources and integrate the information into a written report to be presented to the class. Laboratory Objectives: 1. Perform laboratory experiments to reinforce the concepts, to teach basic laboratory techniques, and to prepare for more advanced laboratory work in chemistry, if applicable; 2. Demonstrate proficiency in using computers for the collection, analysis, and graphical display of data; 3. Diagram the structures and provide names for alkanes, alkenes, alkynes, aromatic compounds, alcohols, and ethers; given a chemical formula, draw isomers of that compound; 4. Construct a Lewis structure for any organic molecule and determine the shape, polarity, intermolecular forces, and properties of that molecule; 5. Apply the technique of liquid-liquid extraction in isolating an organic substance; 6. Using a melting point apparatus, determine the melting point and purity of an organic substance; 7. Identify functional groups using qualitative analysis and investigate their chemical properties; 8. Construct and identify chiral compounds; distinguish between enantiomers, diastereomers, and meso compounds; 9. Identify different types of carbohydrates using qualitative analysis and investigate their chemical properties; 10. Ferment sugars to produce ethanol; apply the technique of distillation to isolate ethanol; 11. Synthesize two esters of salicylic acid: aspirin and oil of wintergreen; 12. Apply the technique of thin-layer chromatography to separate compounds in over the counter medications; 13. Investigate physical and chemical properties of fats and oils; 14. Synthesize soap and explore its properties; 15. Isolate and identify amino acids using paper chromatography; investigate the properties of amino acids and proteins; 16. Analyze the effects of enzyme concentration, temperature, pH, and inhibitors on enzyme activity; 17. Use gel electrophoresis to separate compounds; develop the technique of micropipetting; 18. Identify unknown DNA using gel electrophoresis and determine the number of base pairs using a standard curve; 19. Extract DNA from a fruit or vegetable; 20. Describe the systems which control acid-base balance in the blood; explain the function of the lungs and kidneys in maintaining constant blood pH; 21. Exhibit cooperative and individual skills in the collection and analysis of data; 22. Develop clear, cogent reporting of experimental observations, analysis and conclusions using the scientific method. Methods of Evaluation Essay Examinations Objective Examinations Problem Solving Examinations Projects Reports Skill Demonstrations Reading Assignments 1. Read a section from the textbook or other printed material on proteins. Be prepared to participate in class discussion and to complete assigned problems. 2. Read the experiment on isolation of caffeine and be prepared to perform and answer questions on the experiment. Writing, Problem Solving or Performance 1. Collect data, analyze data, and prepare a written laboratory report on the isolation of caffeine experiment. 2. On a worksheet, write a chemical reaction for the preparation of methyl acetate. Other (Term projects, research papers, portfolios, etc.) Perform research on a topic using library or internet resources. Integrate the information with chemistry concepts and synthesize a written report to be presented to the class. Methods of Instruction Laboratory Lecture/Discussion Distance Learning Other materials and-or supplies required of students that contribute to the cost of the course.
Course Identification Numbering System (C-ID)
...CHEM 101 CHEM 0002A CHEM 102 CHEM 0002B CHEM 110 CHEM 0001A CHEM 110 CHEM...
Transferable Courses to the UC System
...series from CHEM 0001A & CHEM 0001B and CHEM 0002A & CHEM 0002B ), ( CHEM 0003A & CHEM 0003B...
